|
KMID : 0613820110210071016
|
|
Journal of Life Science
2011 Volume.21 No. 7 p.1016 ~ p.1024
|
|
|
Biological Activity of Methanolic Extract from Ganoderma lucidum, Momordica charantia, Fagopyrum tataricum, and Their Mixtures
|
|
Cha Jae-Young
Jin Jong-Sung
Cho Young-Su
|
|
|
Abstract
|
|
|
|
The concentrations of bioactive material (polyphenolics and flavonoids) and the biological activities of antioxidative (DPPH [α,α’-diphenyl-β-picrylhydrazyl] free radical scavenging activity, peroxidation of rat liver microsome, and Fe/Cu reducing power), α-glucosidase inhibition, tyrosinase inhibition, and fibrinolytic activity were tested by in vitro experimental models using 70% methanolic extract from Ganoderma lucidum, Momordica charantia, Fagopyrum tataricum and their mixtures. The highest yield and the concentrations of polyphenolics and flavonoids were shown in the mixture extract. Mixture extract was shown to have the highest activities of α-glucosidase inhibition and tyrosinase inhibition, fibrinolytic, DPPH free radical scavenging, and Fe/Cu reducing power in a concentration-dependent manner. From these results, mixture methanol extract was shown to have the most potent bioactive properties and to contain large amounts of biological materials such as polyphenolics and flavonoids. This mixture could be a good dietary supplement material candidate, such as for antidiabetic functional foods.
|
|
|
KEYWORD
|
|
|
Ganoderma lucidum, Momordica charantia, Fagopyrum tataricum, α-glucosidase
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|